The research of this topic is committed to improving children's awareness of human knowledge. At the same time, the combination of audio-visual interactive picture books to enhance children's interest in body cognition, so as to understand the body structure, learn to protect themselves, which will be the main direction of the future digital publication design. The content of this digital publication is created through many rhetoric such as metaphor and personification. The book adopts the traditional folding book, which can better show a lot of body knowledge when it is unfolded. In terms of APP program, AR technology is adopted, which makes the style of the publication richer, more playable and more novel, thus greatly enhancing the interest of popular science people. The content of this digital publication is created through many rhetoric such as metaphor and personification. The book adopts the traditional folding book, which can better show a lot of body knowledge when it is unfolded. In terms of APP program, AR technology is adopted, which makes the style of the publication richer, more playable and more novel, thus greatly enhancing the interest of popular science people.