Aiming at the safety supervision problems of traditional disinfection products, this disinfection system applies artificial intelligence, big data and Internet of things technology to develop a high reliable safety disinfection system with multiple autonomous perception of the human body, which can realize the safety and efficiency of disinfection. The system development is based on PaddlePaddle (Baidu Flying Paddle) platform and consists of three parts: self-induction disinfection device, bottom navigation system and Internet of Things intelligent terminal. Its innovation points are mainly reflected in disinfection self-induction and self-processing based on multi-sensor fusion, intelligent scheme calculation based on Hadoop, remote supervision of Internet of Things, and self-exploration navigation based on laser SLAM, at the same time, image recognition based on BP neural network and intelligent speech interaction based on natural language processing are used to make the system more intelligent. The project has independent intellectual property rights, all functions have been tested by a third party, the hardware has entered the pilot stage, the software platform has been released online, and the project has no similar functional products for the time being. At the same time, this work has been approved two patents, three software copyrights.